About FIP

Cracking the Code: Is FIP Warriors Legit?

Discover the truth about FIP Warriors: Is it a legit solution for Feline Infectious Peritonitis (FIP)? Uncover expert insights, real-life experiences, and the critical factors to consider when evaluating alternative treatments. Your cat’s well-being depends on informed decisions.

What is FIP Warriors

In recent years, one name has stirred both hope and skepticism among cat owners – “FIP Warriors”. FIP Warriors is a community of cat owners and advocates dedicated to raising awareness and providing support for cats diagnosed with Feline Infectious Peritonitis (FIP). In this article, we’ll delve into the world of FIP Warriors, addressing the burning question: Is FIP Warriors legit?

Is FIP Warriors Legit?

FIP Warriors revolves around the use of GS-441524, a drug that has shown potential in treating FIP. Up to now, FIP Warriors and its admins helped countless FIP cats and so many cats’ parents. It’s true that this community bought FIP parents hope to save their baby. However, given the GS 441524 patent is still unavailable for animal usage, any supplier of GS-441524 IS with a legitimate issue. So the answer is negative.

FIP Warriors claiming that other suppliers are scams and with low quality.

FIP Warriors is a reseller at high price

1. Someone post on one of their groups seeking FIP treatment.

2. Admins played a role of cat owners and enthusiastic helpers chime in, respond either publicly or privately using languages such as ‘I have pm’ed you’. Admin are assigned territories and have sales targets. Other Admins play the role of cat owners and responding to the posts to validate what the selling admin claims.

3. Cat’s owners are steered towards an ‘approved’ brand based on their budget and willingness to pay. If they can afford higher price products, Mutian is usually offered as the default choice. If they have limited funds, then a low price brand is offered. Either way, only the brands that have entered into commission paying agreements are promoted to cat owners. “

Advice to parents

Make GS 441524 formulation on your own

If you may find a lab or alike, it’s easy and affordable to make the injection and pill on your own. May Find how to make GS 441524 formulation here.

Find a reliable source with affordable price

Top 5 supplier is shared here.

How Do Cats Get FIP: the Causes and Risk Factors

We often encounter concerned cat owners seeking answers about Feline Infectious Peritonitis (FIP). This complex disease can be devastating, and understanding how cats contract FIP is crucial to its prevention and management. In this comprehensive guide, we will delve into the causes, risk factors, clinical signs, diagnosis, and prevention of FIP, shedding light on this enigmatic feline disease.

What Is FIP?

Feline Infectious Peritonitis, or FIP, is a formidable adversary in the world of feline health. It is caused by a coronavirus called feline coronavirus (FCoV). Not all FCoV infections lead to FIP; in fact, most result in a benign, intestinal infection. However, in a small percentage of cases, FCoV can mutate into FIP, leading to severe illness.

Before we explore how cats contract FIP, let’s understand the role of feline coronavirus (FCoV). FCoV is relatively common among cats and is typically a benign, intestinal infection. Most cats that contract FCoV experience mild or no symptoms and eventually clear the virus from their system.

microscopic shot of a virus

Modes of Transmission

So, how do cats get FIP and is it contagious to other cats? The primary mode of transmission is through the fecal-oral route. Cats can become infected by coming into contact with the feces of an infected cat, either through shared litter boxes, grooming, or environmental contamination. FCoV can survive in the environment for extended periods, making it a persistent threat.

Additionally, direct cat-to-cat transmission is possible through behaviors such as biting or close contact. This is especially relevant in multi-cat households or environments with a high cat population density.

Can My Indoor Cat Get FIP?

Not all cats exposed to FCoV will develop FIP, and it’s natural to wonder, “Can my indoor cat get FIP?” While indoor cats have a reduced risk compared to outdoor cats, FIP can still affect them if they come into contact with the virus. Factors that increase the risk of FIP include:

Genetic Predisposition: Some cats may have genetic factors that make them more susceptible to FIP.

-Crowded Living Conditions: Overcrowding and high cat population density can increase the likelihood of FCoV transmission.

Stress: Stress weakens the immune system and can make a cat more susceptible to FIP.

-Weakened Immune System: Cats with compromised immune systems are at a higher risk.

Clinical Signs of FIP

Understanding how cats contract FIP is essential, but recognizing the clinical signs is equally important. FIP can manifest in two primary forms: effusive (wet) and non-effusive (dry). Common symptoms include:

– Fever

– Weight Loss

– Lethargy

– Distended Abdomen (in wet FIP)

– Neurological Signs (in some cases)

These symptoms can be subtle and easily mistaken for other illnesses, making FIP a challenging disease to diagnose definitively.

Diagnosing FIP can be complex and often requires multiple diagnostic tests. Veterinarians use blood tests, fluid analysis, and sometimes tissue biopsies to reach a diagnosis. However, even with these tools, FIP remains a challenging disease to confirm definitively.

If you suspect your cat has FIP, it’s crucial to consult with a veterinarian promptly. Early intervention can make a significant difference in managing the disease.

Preventing FIP and Its Spread to Other Cats

Preventing FIP and its spread to other cats centers around minimizing the risk of FCoV exposure and supporting your cat’s immune system. Here are some preventive measures:

Reducing Stress: Create a low-stress environment for your cat.

Maintaining Good Hygiene: Practice good hygiene, especially in multi-cat households.

Isolating Infected Cats: If one of your cats is diagnosed with FIP, isolate them to prevent transmission.

Vaccination (if applicable): Some vaccines may help reduce the risk of FIP and its spread to other cats, but their efficacy can vary.

At last

Understanding how cats contract FIP is a vital step in managing and preventing this challenging disease, especially if you have concerns about FIP being contagious to other cats. While FIP can be devastating, early detection and supportive care can improve a cat’s quality of life. Responsible pet ownership, regular veterinary check-ups, and prompt action if FIP is suspected are essential in the battle against this complex disease.

For further information on FIP and its prevention, consult your veterinarian and consider the following resources:

Remember, your dedication and vigilance as a cat owner play a pivotal role in keeping your feline friend healthy and happy while preventing the spread of FIP to other cats.

What is FIP in cats: Understanding the Deadly Disease

Feline Infectious Peritonitis (FIP) is a devastating illness that affects cats worldwide, causing significant distress for both the pets and their owners. But fear not, as knowledge and support can make a world of difference. In this comprehensive guide, we will delve into the intricacies of FIP, exploring its causes, symptoms, and treatments. We will also shed light on how you can provide the best care possible for your furry companion, offering tips on nutrition, environmental enrichment, and emotional support. Whether you are a cat owner searching for answers or a veterinary professional seeking to expand your knowledge, this article is your go-to resource for all things FIP. So, let’s embark on this journey together and empower ourselves to give our feline friends the love and care they deserve in the face of this deadly disease.

httpss://www.youtube.com/watch?v=4RocYMUo_w8

What is FIP (Feline Infectious Peritonitis)?

Feline infectious peritonitis (FIP) is the name given to a common and aberrant immune response to infection with feline coronavirus (FCoV).

FIP is a viral disease that affects cats, causing a range of symptoms and often leading to fatal outcomes. FIP is caused by a mutated form of the feline coronavirus, which is a common virus that infects many cats without causing any serious health issues. However, in some cases, the virus mutates and is then able to cause FIP. This mutation occurs within the cat’s own body, making it difficult to prevent or predict. Once the mutated virus is present, it can lead to a systemic inflammatory response that affects various organs, such as the liver, kidneys, and brain.

The symptoms of FIP can vary depending on the form of the disease, which can be either “wet” or “dry.” In the wet form, fluid accumulates in the cat’s abdomen or chest, leading to distension and difficulty breathing. In the dry form, granulomas, or small inflammatory lesions, form in different organs, causing a range of symptoms, including weight loss, fever, and neurological abnormalities. It’s important to note that FIP can affect cats of all ages, but it is more common in young kittens and cats with weakened immune systems.

microscopic shot of a virus

Causes and Transmission of FIP

The exact causes of FIP are still not fully understood, but it is believed to be a result of a combination of factors, including the cat’s immune response, genetics, and the presence of the feline coronavirus. While the feline coronavirus is highly contagious among cats, not all cats who are exposed to it will develop FIP. The mutation of the virus within the cat’s body plays a crucial role in the development of the disease.

FIP can be transmitted through direct contact with an infected cat’s bodily fluids, such as saliva or nasal discharge. It can also be transmitted through indirect contact, such as sharing litter boxes or food bowls. The virus can survive in the environment for several weeks, making it important to practice good hygiene and sanitation measures, especially in multi-cat households or catteries. It’s worth noting that FIP is not contagious to humans or other species, so there is no need to worry about transmission to yourself or other pets.

Clinical FIP symptom

FIP can manifest in three forms: wet (effusive), dry (non-effusive) and neuro/ocular FIP

  • Wet FIP is characterized by the accumulation of fluid in the abdomen or chest, leading to breathing difficulties and a distended abdomen.
  • Dry FIP involves granulomas—small collections of inflammatory cells—in various organs. These granulomas can interfere with the function of the affected organs, leading to a wide range of symptoms.
  • There’s also a form that affects the brain and nervous system, known as neurological FIP, which can cause neurological symptoms such as seizures and loss of coordination.

Diagnosis

Diagnosing effusive FIP

Diagnosis of the effusive form of the disease has become more straightforward in recent years. Detection of viral RNA in a sample of the effusion (liquid drained from body), such as by reverse transcription polymerase chain reaction (RT-PCR) is diagnostic of effusive FIP. However, that does require that a sample be sent to an external veterinary laboratory. Within the veterinary hospital there are a number of tests which can rule out a diagnosis of effusive FIP within minutes:

  1. Measure the total protein in the effusion: if it is less than 35 g/L, FIP is extremely unlikely.
  2. Measure the albumin to globulin ratio in the effusion: if it is over 0.8, FIP is ruled out; if it is less than 0.4, FIP is a possible—but not certain—diagnosis
  3. Examine the cells in the effusion: if they are predominantly lymphocytes (a type of white blood cell), then FIP is excluded as a diagnosis.

Diagnosing non-effusive FIP

Non-effusive FIP is more difficult to diagnose than effusive FIP because the clinical signs tend to be more vague and varied: the list of differential diagnoses is therefore much longer. Non-effusive FIP diagnosis should be considered when the following criteria are met:

  1. History: the cat is young (under 2 years old) and purebred: over 70% of cases of FIP are in pedigree kittens.
  2. History: the cat experienced stress such as recent neutering or vaccination.
  3. History: the cat had an opportunity to become infected with FCoV, such as originating in a breeding or rescue cattery, or the recent introduction of a purebred kitten or cat into the household.
  4. Clinical signs: the cat has become anorexic or is eating less than usual; has lost weight or failed to gain weight; has a fever of unknown origin; intra-ocular signs; jaundice.
  5. Biochemistry: hypergammaglobulinaemia; raised bilirubin without liver enzymes being raised.
  6. Hematology: lymphopenia; non-regenerative—usually mild—anaemia.
  7. Serology: the cat has a high antibody titre to FCoV: this parameter should be used with caution, because of the high prevalence of FCoV in breeding and rescue catteries.
  8. Non-effusive FIP can be ruled out as a diagnosis if the cat is seronegative, provided the antibody test has excellent sensitivity. In a study which compared various commercially available in-house FCoV antibody tests,[19] the FCoV Immunocomb (Biogal) was 100% sensitive; the Speed F-Corona rapid immunochromatographic (RIM) test (Virbac) was 92.4% sensitive and the FASTest feline infectious peritonitis (MegaCor Diagnostik) RIM test was 84.6% sensitive.

Treatment Options for FIP

Traditional Treatment Options

Traditional treatment for FIP is mainly supportive and includes fluid therapy to address dehydration and anti-inflammatory drugs to control inflammation and fever. Fluid therapy can help replace the fluids lost due to vomiting, diarrhea, or lack of appetite, while anti-inflammatory drugs can help reduce the inflammation caused by the disease. However, these treatments do not address the underlying cause of the disease and are mainly aimed at improving the cat’s quality of life.

GS-441524

A 2018 study published by Murphy et al. demonstrated that GS-441524, a less chemically complex parent nucleoside (also patented by Gilead), was highly effective against experimentally induced FIP at a dosage of 4.0 mg/kg subcutaneously every 24 h for 12 weeks (84 days) in 10 laboratory cats. This gives us hope to treat FIP cats.

Experimental Treatments and Clinical Trials

There are ongoing clinical trials exploring new treatments for FIP. Participating in these trials can provide access to cutting-edge treatments and contribute to our understanding of the disease. I’ve had patients who have participated in these trials, and while it’s not a guarantee of a cure, it does offer hope for a potential breakthrough in FIP treatment.

Preventing FIP in Cats

Preventing FIP can be challenging, as the disease is complex and multifactorial. Minimizing stress and maintaining good hygiene are key aspects of prevention. Providing a clean and sanitary environment for your cat, including regular litter box cleaning and disinfection of shared spaces, can help reduce the risk of transmission. If you have multiple cats, consider separating them temporarily if one of them is diagnosed with FIP to prevent further spread of the virus.

Vaccination against feline coronavirus is available, but its effectiveness in preventing FIP is still a topic of debate. Consult with your veterinarian to understand the benefits and limitations of vaccination in your cat’s specific situation. It’s worth noting that vaccination cannot guarantee complete protection against FIP, especially in cats with a higher risk of developing the disease.

Conclusion and Resources for Further Information

FIP is a challenging and devastating disease, but with knowledge, support, and proper care, you can make a significant difference in your feline friend’s life. Understanding the causes, symptoms, and treatment options of FIP is essential for providing the best care possible. Remember to work closely with your veterinarian, who can guide you through the diagnosis and treatment process. Stay informed and seek support from trusted sources, such as reputable veterinary websites, support groups, and scientific publications. Together, we can empower ourselves to give our feline friends the love and care they deserve in the face of this deadly disease.

For further information and resources on FIP, consider visiting the following websites:

[The Winn Feline Foundation]

[Cornell Feline Health Center]

[American Association of Feline Practitioners]

[FIP Doctor saves 10,000+ FIP cats]

Remember, knowledge is power, and by staying informed, you can be a strong advocate for your feline friend and help create a better future for cats affected by FIP.

dog, pet, cat-1532627.jpg

FIP Cat Treatment: The Life-Saving Information

I. Introduction

Feline Infectious Peritonitis (FIP) is a complex and often misunderstood disease that affects cats. We’ve seen firsthand the confusion and distress it can cause among cat owners. This article aims to shed light on FIP and its treatment, providing comprehensive information that you may not always receive from your vet. It’s a journey of understanding, a journey of hope, and a journey of love for our feline friends.

II. Understanding FIP in Cats

What is FIP?

FIP is a viral disease caused by certain strains of the feline coronavirus. It’s an aggressive disease that can affect cats of all ages, but it’s more common in young cats and kittens. The virus can mutate in the cat’s body, leading to an immune response that results in inflammation in various parts of the body. This inflammation can cause a wide range of symptoms and complications, making FIP a serious and often fatal disease.

Feline infectious peritonitis virus

Types of FIP

FIP can manifest in three forms: wet (effusive), dry (non-effusive) and neuro/ocular FIP

  • Wet FIP is characterized by the accumulation of fluid in the abdomen or chest, leading to breathing difficulties and a distended abdomen.
  • Dry FIP involves granulomas—small collections of inflammatory cells—in various organs. These granulomas can interfere with the function of the affected organs, leading to a wide range of symptoms.
  • There’s also a form that affects the brain and nervous system, known as neurological FIP, which can cause neurological symptoms such as seizures and loss of coordination.
Summary of the systemic clinical signs and pathologies associated with FIP. FIP is well known to be a systemic infection with a diverse presentation. From httpss://www.mdpi.com/1519424

Symptoms of FIP

Symptoms of FIP can vary widely and may include fever, weight loss, loss of appetite, and lethargy. Wet FIP often causes a distended abdomen due to fluid accumulation, while dry FIP symptoms depend on the organs affected. For instance, if the liver is affected, the cat may become jaundiced, while lung involvement may cause breathing difficulties. Neurological FIP can lead to changes in behavior, seizures, and loss of coordination. It’s important to remember that these symptoms can also be seen in many other diseases, which is why FIP can be difficult to diagnose.

III. The Diagnosis Process

Challenging to Diagnose FIP

Diagnosing FIP can be challenging due to its nonspecific symptoms. Vets often rely on a combination of clinical signs, blood tests, and analysis of any accumulated fluid. For instance, a blood test may reveal anemia and increased proteins in the blood, while analysis of the fluid from wet FIP may show high protein levels and specific types of cells. However, these findings are not exclusive to FIP and can be seen in other diseases as well.

FIP is often misdiagnosed because its symptoms can mimic other diseases. I remember a case where a cat was initially diagnosed with liver disease due to jaundice and weight loss. However, further testing revealed it was actually suffering from dry FIP. This highlights the importance of comprehensive diagnostic testing in ensuring an accurate diagnosis.

The Importance of a Second Opinion

Given the complexities of diagnosing FIP, it’s crucial to seek a second opinion if your cat’s condition doesn’t improve or worsens despite treatment. A second opinion can provide a fresh perspective and may uncover aspects of the case that were initially overlooked. It’s always better to have more information when dealing with a disease as complex as FIP.

IV. Treatment Options for FIP

Traditional Treatment Options

Traditional treatment for FIP is mainly supportive and includes fluid therapy to address dehydration and anti-inflammatory drugs to control inflammation and fever. Fluid therapy can help replace the fluids lost due to vomiting, diarrhea, or lack of appetite, while anti-inflammatory drugs can help reduce the inflammation caused by the disease. However, these treatments do not address the underlying cause of the disease and are mainly aimed at improving the cat’s quality of life.

GS-441524

A 2018 study published by Murphy et al. demonstrated that GS-441524, a less chemically complex parent nucleoside (also patented by Gilead), was highly effective against experimentally induced FIP at a dosage of 4.0 mg/kg subcutaneously every 24 h for 12 weeks (84 days) in 10 laboratory cats. This gives us hope to treat FIP cats.

Experimental Treatments and Clinical Trials

There are ongoing clinical trials exploring new treatments for FIP. Participating in these trials can provide access to cutting-edge treatments and contribute to our understanding of the disease. I’ve had patients who have participated in these trials, and while it’s not a guarantee of a cure, it does offer hope for a potential breakthrough in FIP treatment.

V. What Vets Don’t Often Tell You

The Reality of FIP Prognosis

FIP is often considered fatal, but it’s important to remember that every cat is unique, and some do respond well to treatment. I’ve seen cases where cats with FIP have lived for months or even years with a good quality of life. While it’s important to be realistic about the prognosis, it’s equally important to maintain hope and celebrate every moment with your beloved pet.

The Cost of FIP Treatment

The cost of GS-441524 formulation to treat Feline Infectious Peritonitis cats can vary widely depending on several factors.

  • Dosage and Treatment Duration: The cost of GS-441524 is often calculated based on the required dosage and the duration of treatment. Cats with FIP may require treatment for several weeks or even months. The longer the treatment duration and the higher the dosage, the more expensive the treatment can be.
  • Concentration of the Medication: GS-441524 may be available in different concentrations, and the cost can vary depending on the concentration used. Higher concentrations may be more expensive but can also allow for smaller volumes to be administered.
  • Source of the Medication: The source from which you obtain GS-441524 can impact the cost. Some cat owners obtain the medication through compounding pharmacies, while others may participate in clinical trials where the medication is provided as part of the study. The cost can also vary if you purchase it from a trusted online source.

FIP Doctor provides a website to calculate daily and monthly dosage and cost based on the type of FIP and weight.

The Emotional Toll of FIP

Dealing with a cat’s FIP diagnosis can be emotionally draining. I’ve seen many owners struggle with feelings of guilt, sadness, and anxiety. It’s crucial to seek support from friends, family, or professional counselors during this time. Remember, it’s okay to feel overwhelmed and it’s okay to ask for help. You’re not alone in this journey.

VI. Caring for a Cat with FIP at Home

Managing Symptoms at Home

Making your cat comfortable at home involves managing their symptoms. This can include providing a warm and quiet place to rest, encouraging them to eat, and giving them plenty of love and attention. I’ve had clients who’ve set up special areas in their homes for their cats, complete with heated beds and favorite toys. These small gestures can make a big difference in your cat’s comfort and well-being.

Dietary Considerations

Cats with FIP often lose their appetite, so it’s important to offer them palatable, high-quality food. Warming up their food or offering a variety can sometimes help stimulate their appetite. I’ve had clients who’ve had success with feeding their cats homemade meals, under the guidance of a veterinary nutritionist. It’s all about finding what works for your cat and providing them with the nutrition they need.

Regular Vet Check-ups and Early Detection

Regular vet check-ups can help detect any health issues early, including FIP. Early detection can lead to more effective management of the disease. I’ve had cases where early detection of FIP has allowed for early intervention and improved outcomes. It’s a testament to the importance of regular vet visits and proactive healthcare.

Preventing the Spread of FIP

In multi-cat households, it’s important to isolate a cat diagnosed with FIP to prevent the spread of the virus. Regular cleaning and disinfection are also crucial. I’ve had clients who’ve successfully managed to prevent the spread of FIP in their multi-cat households through diligent hygiene practices and careful management. It’s a challenging task, but it’s certainly possible with the right measures.

VII. Conclusion

Understanding FIP and its treatment can be a complex journey, but remember, you’re not alone. Stay informed, ask questions, and don’t lose hope. Feel free to reach out with any questions or share your experiences—we’re all in this together. And remember, every moment with your beloved pet is precious. Cherish them, love them, and know that you’re doing your best for them.

Remember, this article is intended to provide general information about FIP and its treatment. Always consult with your vet for advice tailored to your cat’s specific situation.

close up photo of cute sleeping cat

FIP and GS-441524

1.What is Feline infectious peritonitis (FIP)?

Feline infectious peritonitis (FIP) is the name given to a common and aberrant immune response to infection with feline coronavirus (FCoV).[1]

FCoV is a virus of the gastrointestinal tract. Most infections are either asymptomatic or cause diarrhea, especially in kittens, as maternally derived antibody wanes at between 5 and 7 weeks of age. The virus is a mutation of feline enteric coronavirus (FECV). From the gut, the virus very briefly undergoes a systemic phase,[2] before returning to the gut where it is shed in the feces.

The pathogenesis of FIP is complex. There is a general consensus that FIPVs arise from mutations enabling them to enter or replicate more successfully in monocytes (a type of white blood cell). However, many aspects of virus–host interactions affecting the disease remain uncertain, such as the factors that influence disease form (wet or dry), outcome (death or resistance), and host susceptibility.[3]

2.FIP Stage (Wet, Dry, Ocular and Neurological)

There are two main forms of FIP: effusive (wet) and non-effusive (dry). While both types are fatal, the effusive form is more common (60–70% of all cases) and progresses more rapidly than the non-effusive form.

Wet FIP is characterized by the accumulation of large amounts of inflammatory fluid either in the abdominal cavity and/or chest cavity. Involvement of the central nervous system (CNS) and eyes is relatively uncommon in the wet form of FIP. Other symptoms include lack of appetite, fever, weight loss, jaundice, and diarrhea.

The dry form of FIP is characterized, not by diffuse inflammation and fluid effusion, but rather by less numerous and larger tumor-like lesions (i.e., granulomas) in organs (e. g., kidney, cecum, colon, liver, lung, lymph nodes) within the abdominal or thoracic cavities, or in the eyes and brain. Whereas the brain and/or eyes are only involved in 9% of the cases, neurological and-or ocular disease is seen as the main presenting clinical sign in 70% of cats with dry FIP.[4]

3.How to diagnose FIP cat?

3.1. Diagnosing effusive FIP

Within the veterinary hospital there are a number of tests which can rule out a diagnosis of effusive FIP within minutes:

  1. Measure the total protein in the effusion: if it is less than 35g/L, FIP is extremely unlikely.
  2. Measure the albumin to globulin ratio in the effusion: if it is over 0.8, FIP is ruled out; if it is less than 0.4, FIP is a possible—but not certain—diagnosis.[5]
  3. Examine the cells in the effusion: if they are predominantly lymphocytes (a type of white blood cell), then FIP is excluded as a diagnosis.

3.2. Diagnosing non-effusive FIP

Non-effusive FIP is more difficult to diagnose than effusive FIP because the clinical signs tend to be more vague and varied: the list of differential diagnoses is therefore much longer. Non-effusive FIP diagnosis should be considered when the following criteria are met:[5]

  1. History: the cat is young (under 2 years old) and purebred: over 70% of cases of FIP are in pedigree kittens.
  2. History: the cat experienced stress such as recent neutering or vaccination
  3. History: the cat had an opportunity to become infected with FCoV, such as originating in a breeding or rescue cattery, or the recent introduction of a purebred kitten or cat into the household.
  4. Clinical signs: the cat has become anorexic or is eating less than usual; has lost weight or failed to gain weight; has a fever of unknown origin; intra-ocular signs; jaundice.
  5. Biochemistry: hypergammaglobulinaemia; raised bilirubin without liver enzymes being raised.
  6. Hematology: lymphopenia; non-regenerative—usually mild—anaemia.
  7. Serology: the cat has a high antibody titre to FCoV: this parameter should be used with caution, because of the high prevalence of FCoV in breeding and rescue catteries.

4.How to deal with FIP?

An experimental drug called GS-441524 was used in a field experiment of 31 cats. After 25 days, five cats had died, eight had been cured and subsequently relapsed, and 18 had been cured without any subsequent relapses. The eight who relapsed were treated again, some with higher doses. Of these eight, one died and seven were cured, meaning that 25 of the 31 cats were ultimately cured of FIP. Although the drug is not yet (as of 2019) commercially available in the United States, this study is considered very promising and may lead to commercially available medication for the treatment of FIP.[6] GS-441524 is available at >99% purity commercially from FIP Doctor as injection and tablet formulation (www.fipdoctor.com).


Reference

[1] Addie, D.; Belák, S.; Boucraut-Baralon, C.; Egberink, H.; Frymus, T.; Gruffydd-Jones, T.; Hartmann, K.; Hosie, M. J.; Lloret, A.; et al. (2009-07-11). “Feline infectious peritonitis. ABCD guidelines on prevention and management”. Journal of Feline Medicine and Surgery. 11 (7): 594–604. doi:10.1016/j.jfms.2009.05.008. PMC 7129471. PMID 19481039

[2] Porter, E.; Tasker, S.; Day, M. J.; Harley, R.; Kipar, A.; Siddell, S. G.; Helps, C. R. (2014-04-25). “Amino acid changes in the spike protein of feline coronavirus correlate with systemic spread of virus from the intestine and not with feline infectious peritonitis”. Veterinary Research. BiomedCentral. 45 (1): 49. doi:10.1186/1297-9716-45-49. PMC 4006447. PMID 24767677

[3] Pedersen, N. C. (August 2014). “An update on feline infectious peritonitis: virology and immunopathogenesis”. The Veterinary Journal. 201 (2): 123–132. doi:10.1016/j.tvjl.2014.04.017. PMC 7110662. PMID 24837550.

[4]httpss://ccah.vetmed.ucdavis.edu/sites/g/files/dgvnsk4586/files/inline-files/Neurological%20FIP%20v5%281%29.pdf

[5] “Dr. Addie – What is FIP?”. www.catvirus.com.

[6] Pedersen, N. C.; Perron, M.; Bannasch, M.; Montgomery, E.; Murakami, E.; Liepnieks, M.; Liu, H. (2019-02-13). “Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis”. Journal of Feline Medicine and Surgery. 21 (4): 271–281. doi:10.1177/1098612X19825701. PMC 6435921. PMID 30755068.

Shopping Cart
[]